CDT PhD student's research observes cancer drug uptake in 3D

Cambridge CDT PhD student Marcus Fantham presented his research in Bordeaux and New Orleans, which featured in his recent Nature Photonics paper.

Marcus Fantham, a PhD student within Professor Clemens Kaminski's group at Cambridge, recently published a research paper in collaboration with a materials scientist showing work on so-called "Metal Organic Frameworks" (MOFs) being used as a nano-carrier of cancer drugs. The paper showed MOFs increase the uptake of drug by cells and therefore lower the dose required for effective cancer treatment, reducing the unpleasant side-effects of these drugs.

Marcus said "With my recent work we were able to observe drug uptake in 3D, track it over time on both a short timescale (10 frames/second) and long timescale (over 24 hours), and publish these 3D image stacks in an interactive viewer (using my previous publication FPBioimage)." 

Should you wish to read Marcus' paper, the citation information is below, along with some photos of him presenting his research at the Biophysical Society Annual Meeting 2017 which he attended back in February 2017 in New Orleans.

Citation information is as follows:

Teplensky, M.H., Fantham, M., Li, P., Wang, T.C., Mehta, J.P., Young, L.J., Moghadam, P.Z., Hupp, J.T., Farha, O.K., Kaminski, C.F. and Fairen-Jimenez, D., 2017. Temperature Treatment of Highly Porous Zirconium-Containing Metal-Organic Frameworks Extends Drug Delivery Release. Journal of the American Chemical Society.

Marcus in BordeauxMarcus in New Orleans